Searchable abstracts of presentations at key conferences in endocrinology

ea0063p486 | Calcium and Bone 2 | ECE2019

Dynamic thiol/disulfide homeostasis and oxidant status in patients with hypoparathyroidism

Koca Arzu Or

Purpose: In this study, we aimed at determining the dynamic thiol/disulfide homeostasis and oxidant balance, and investigating the relation of these parameters to the severity of the disease and the serum calcium levels.Material and method: 55 patients with iatrogenic hypoparathyroidism follow-ups, and 40 healthy volunteers were included in the study. The blood dynamic thiol/sulfide balance, Total Antioxidant Status (TAS), Total Oxidant Status (TOS), Par...

ea0063p618 | Diabetes, Obesity and Metabolism 2 | ECE2019

The effects of hyperinsulinemia on cochlear functions

Koca Arzu Or

Purpose: Hyperinsulinemia is the metabolic change, which is related to the cochleovestibular diseases the most. It is thought that undiagnosed deafness is highly probable in individuals with prediabetic hyperinsulinemia. We aimed at investigating the results of hearing function test in hyperinsulinemic individuals.Material and Method: 164 patients were included in the study, which was designed as a prospective research, 76 of which were in case group and...

ea0063p727 | Pituitary and Neuroendocrinology 2 | ECE2019

Is idiopathic mild hyperprolactinemia a cardiovascular risk factor?

Koca Arzu Or

Aim: In our study, we aimed at investigating cardiovascular risk predictability by conducting arterial stiffness measurement in patients with idiopathic hyperprolactinemia.Material – Method: The biochemical parameters and arterial stiffness analyses of 54 patients with idiopathic hyperprolactinemia, who had applied to our polyclinic in 2017 and 2018, and 55 healthy volunteers having similar characteristics with regard to age, sex and body mass index...

ea0063ep155 | Thyroid | ECE2019

Transient elevation of CA 19-9 due to cessation of levothyroxine in a patient with Hashimoto’s thyroiditis

Koca Arzu Or , Altay Mustafa

Serum CA 19-9 (carbohydrate antigen 19-9) is a tumor marker of monosialoganglioside structure. Its level is frequently measured for screening purposes in daily practice by physicians, while its main use is in the study of tumor recurrence and follow-up of recurrences. Although significant elevations in CA 19-9 levels cause suspicion of malignancy, an underlying malignant disease may not always be determined and benign pathologies may also be seen. A 45-year-old female patient ...

ea0063p378 | Thyroid 1 | ECE2019

Should the dose of levothyroxine be changed in hypothyroidism patients fasting during Ramadan?

Koca Arzu Or , Dağdeviren Murat , Altay Mustafa

Objective: Muslims worship by fasting from pre-dawn (suhoor) until sunset (iftar) for 30 days in the religious month of Ramadan. In addition to prolonged hunger, patients fasting with a diagnosis of hypothyroidism take their doses of levothyroxine outside of daytime fasting hours. This study compares thyroid functions of fasting hypothyroidism patients with the values before Ramadan.Methods: One hundred patients aged 18–65 years were included in the...

ea0063p496 | Calcium and Bone 2 | ECE2019

A new and effective treatment option for challenging chronic hypoparathyroidism cases: Alternate-day dosing regimen

Akkan Tolga , Dagdeviren Murat , Or Koca Arzu , Ertugrul Derun Taner , Altay Mustafa

Objective: In chronic hypoparathyroidism, conventional therapy consists of oral calcium supplements and active vitamin D analogs but some patients cannot achieve treatment goals despite the high dose of oral calcium supplementation. Therefore, parathyroid gland transplantation and recombinant human PTH have been investigating as new therapeutic options. Calcium absorption from intestinal cells occurs by transcellular path and paracellular path. Transcellular absorption occurs ...

ea0063p773 | Thyroid 2 | ECE2019

Evaluation of oxidative stress parameters in subacute thyroiditis patients

Dağdeviren Murat , Koca Arzu Or , Akkan Tolga , Ateş İhsan , Neşelioğlu Salim , Erel Ozcan , Altay Mustafa

Objective: The aim of our study was to determine whether there is a relationship between oxidative stress parameters and subacute thyroiditis.Material and methods: The study included 55 subacute thyroiditis patients and 30 healthy volunteers. Total antioxidant status (TAS), total oxidant status (TOS), paraoxonase (PON) and thiol/disulfide homeostasis parameters were measured by a novel and automated assay in the patient and control groups.<p class="a...

ea0070aep141 | Bone and Calcium | ECE2020

Identifying clinical characteristics of hypoparathyroid patients in turkey: The ‘HIPOPARATURK-NET Study’

Konca Degertekin Ceyla , Gogas Yavuz Dilek , Pekkolay Zafer , Ugur Kader , Or Koca Arzu , Topaloğlu Ömercan , Ozdemir Kutbay Nilufer , Aydoğan Ünsal Yasemin , Yilmaz Nusret , Omma Tülay

Hypoparathyroidism is a rare endocrine disorder whose epidemiologic characteristics regarding the cause, clinical course, acute and chronic complications have not been well defined. There is also a substantial geographic variability regarding those parameters, and country-specific local data is scarce.This study was conducted to assess the baseline characteristics, including the demographics, etiologic distribution, disease severity, medications use...